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Updated: Jun 26, 2026

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
[Anterior cruciate ligament reconstruction: indications and techniques]
Victoria B Duthon1, Guy Messerli, Jacques Menetrey
1Service de chirurgie orthopédique et traumatologie de l'appareil moteur, Département de chirurgie HUG, Faculté de médecine 1211 Genève 14. victoria.duthon@hcuge.ch
Abstract:
The anterior cruciate ligament (ACL) is a key structure for the knee joint stability and is frequently injured. Patients can be classified as "low-risk" or "high-risk" to have subsequent knee instability or meniscal injuries. This risk is based on the pre-injury level of sports participation and on the initial knee stability. For low-risk patients (mostly sedentary, senior), conservative treatment with physiotherapy leads to a satisfactory outcome. For high-risk patients (the young, competitive athlete), early ligament reconstruction is mandatory. Numerous ACL reconstruction techniques exist with auto- or allografts. However these guidelines must be adapted to the patient characteristics, motivations and expectations, in order to offer a treatment "a la carte".
