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Related Concept Videos

Structure of Lipids03:38

Structure of Lipids

Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic birds and...
Structure of Lipids03:38

Structure of Lipids

Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic birds and...
Structure of Lipids03:38

Structure of Lipids

Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic birds and...
Liquid–Solid Solutions01:29

Liquid–Solid Solutions

The process of a solid dissolving in a liquid to form a solution is governed by the solubility limit, which is the maximum amount of the solid substance, or solute, that can be dissolved in a specific volume of the liquid or solvent. As the solute dissolves, it reaches a point where no more solute can be dissolved at a given temperature - this is known as the saturation point. However, if further solute is added and it manages to dissolve, the solution becomes supersaturated. Supersaturated...
Solid–Solid Solutions01:24

Solid–Solid Solutions

The temperature-composition phase diagram of two solids, A and B, which are immiscible in the solid phase but form miscible liquids, shows that when the temperature is low, these two exist as separate, pure solids (A and B). As the temperature increases, they transition into a single-phase liquid solution where A and B coexist. Moving from point a1 to a2 in the phase diagram, the composition changes such that solid B begins to separate from the solution, enriching the remaining liquid with A.
What are Lipids?01:38

What are Lipids?

Overview

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Related Experiment Video

Updated: Jun 26, 2026

Neutron Spin Echo Spectroscopy as a Unique Probe for Lipid Membrane Dynamics and Membrane-Protein Interactions
10:02

Neutron Spin Echo Spectroscopy as a Unique Probe for Lipid Membrane Dynamics and Membrane-Protein Interactions

Published on: May 27, 2021

Solution and solid-state NMR of lipids.

Axelle Grelard1, Anthony Couvreux, Cécile Loudet

  • 1CNRS-Université Bordeaux 1, IECB, Pessac, France.

Methods in Molecular Biology (Clifton, N.J.)
|January 24, 2009
PubMed
Summary
This summary is machine-generated.

Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful technique for analyzing lipid structure and dynamics. This method reveals molecular details and membrane properties, crucial for understanding cellular functions.

More Related Videos

NMR Spectroscopy as a Robust Tool for the Rapid Evaluation of the Lipid Profile of Fish Oil Supplements
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NMR Spectroscopy as a Robust Tool for the Rapid Evaluation of the Lipid Profile of Fish Oil Supplements

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A Package of Established Analytical Tools to Investigate the Solid-State Alteration of Lipid-Based Excipients
11:27

A Package of Established Analytical Tools to Investigate the Solid-State Alteration of Lipid-Based Excipients

Published on: August 9, 2022

Related Experiment Videos

Last Updated: Jun 26, 2026

Neutron Spin Echo Spectroscopy as a Unique Probe for Lipid Membrane Dynamics and Membrane-Protein Interactions
10:02

Neutron Spin Echo Spectroscopy as a Unique Probe for Lipid Membrane Dynamics and Membrane-Protein Interactions

Published on: May 27, 2021

NMR Spectroscopy as a Robust Tool for the Rapid Evaluation of the Lipid Profile of Fish Oil Supplements
08:54

NMR Spectroscopy as a Robust Tool for the Rapid Evaluation of the Lipid Profile of Fish Oil Supplements

Published on: May 1, 2017

A Package of Established Analytical Tools to Investigate the Solid-State Alteration of Lipid-Based Excipients
11:27

A Package of Established Analytical Tools to Investigate the Solid-State Alteration of Lipid-Based Excipients

Published on: August 9, 2022

Area of Science:

  • Biochemistry
  • Biophysics
  • Membrane Biology

Background:

  • Lipids are vital for cellular function, involved in signaling pathways and maintaining membrane integrity.
  • Phosphatidyl inositol (PtdIns), cholesterol, and sphingomyelin play key roles in cell membranes.
  • Understanding lipid structure and dynamics is essential for deciphering cellular processes.

Purpose of the Study:

  • To demonstrate the utility of Nuclear Magnetic Resonance (NMR) spectroscopy for analyzing lipid structure and dynamics.
  • To showcase how NMR can elucidate lipid roles in membrane organization and function.

Main Methods:

  • Utilized multinuclear one-dimensional and two-dimensional NMR for liquid-state analysis of extracted lipids.
  • Employed multinuclear solid-state NMR with magic angle spinning for membrane phase and lipid dynamics determination.

Main Results:

  • Liquid-state NMR successfully revealed the molecular structure of lipids dissolved in organic solvents.
  • Solid-state NMR provided insights into membrane phase behavior (lamellar, hexagonal, isotropic) and lipid dynamics (fluid, gel, liquid ordered).
  • NMR experiments elucidated the molecular structure of lipids within different membrane environments.

Conclusions:

  • NMR spectroscopy is a versatile and powerful tool for comprehensive lipid analysis.
  • Both liquid- and solid-state NMR are crucial for understanding lipid structure, dynamics, and their role in membrane organization.