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Related Concept Videos

Neuroplasticity01:01

Neuroplasticity

Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
Plasticity00:58

Plasticity

Plasticity is the property where an object loses its elasticity and undergoes irreversible deformation, even after the deformation forces are eliminated. If a material deforms irreversibly without increasing stress or load, then this is called ideal plasticity. For example, when a force is applied to an aluminum rod, it changes its shape, but it does not return to its original shape once the force is removed. Plastic deformation or ductility is thus a permanent deformation or change in the...
Long-term Potentiation01:25

Long-term Potentiation

Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
LTP can occur when presynaptic neurons...
Long-term Potentiation01:35

Long-term Potentiation

Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Plastic Deformations01:19

Plastic Deformations

Plastic deformation represents a fundamental concept in materials science, which explains the irreversible change in the shape of a material when it experiences stress beyond its elastic capability. This phenomenon is important in structural engineering, especially in designing and analyzing cantilever beams—structures that are securely fixed at one end and bear loads at the opposite end. When these beams are subjected to loads within their elastic range, they will return to their original...
Plastic Deformations01:14

Plastic Deformations

It is essential to understand how structural members behave under plastic deformation when the bending stress exceeds the material's yield strength. This state of deformation permanently alters the shape of the member, in contrast to the linear elastic behavior observed before yielding. The strain at any point in the member is expressed in terms of maximum strain. Notably, the neutral axis, which coincides with the centroid during elastic bending, shifts away from the centroid under plastic...

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Updated: Jun 26, 2026

Slice Patch Clamp Technique for Analyzing Learning-Induced Plasticity
11:56

Slice Patch Clamp Technique for Analyzing Learning-Induced Plasticity

Published on: November 11, 2017

Activity-dependent structural plasticity.

Markus Butz1, Florentin Wörgötter, Arjen van Ooyen

  • 1Bernstein Center for Computational Neuroscience, Universität Göttingen, Bunsenstr. 10, 37073 Göttingen, Germany. mbutz@bccn-goettingen.de

Brain Research Reviews
|January 24, 2009
PubMed
Summary
This summary is machine-generated.

Brain structural plasticity involves more than just synaptic changes, including synapse formation/elimination and axonal re-routing. This review explores spontaneous, experience-dependent, and reactive plasticity for insights into brain repair and memory.

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Inducing Long-Term Plasticity of Intrinsic Neuronal Excitability in Neurons of the Dorsal Lateral Geniculate Nucleus

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Last Updated: Jun 26, 2026

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Inducing Long-Term Plasticity of Intrinsic Neuronal Excitability in Neurons of the Dorsal Lateral Geniculate Nucleus
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Area of Science:

  • Neuroscience
  • Cellular Biology

Background:

  • Brain plasticity extends beyond synaptic strength changes.
  • Recent imaging reveals dynamic structural changes like synapse turnover and axonal remodeling in vivo.
  • Structural plasticity plays a role in network homeostasis, independent of traditional plasticity models.

Purpose of the Study:

  • To review and integrate findings on structural plasticity from historical lesion studies with recent experimental data.
  • To compare different forms of structural plasticity: spontaneous, experience-dependent, and lesion-induced (reactive).
  • To highlight the relevance of understanding neural network reorganization for memory and neurological disease treatment.

Main Methods:

  • Review of historical lesion studies.
  • Analysis of recent time-lapse imaging data from the living brain.
  • Comparative analysis of different plasticity paradigms.

Main Results:

  • Structural plasticity encompasses synapse dynamics, spine motility, and axonal branching.
  • Some structural plasticity contributes to network activity homeostasis.
  • Both developmental and adult brains exhibit reactive structural plasticity following lesions.

Conclusions:

  • Structural plasticity is a fundamental property of the brain, occurring throughout life.
  • Understanding structural plasticity is crucial for deciphering long-term memory mechanisms.
  • Insights into structural plasticity can inform therapeutic strategies for neurological disorders like stroke.