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Fluid dynamics studies of cardiovascular medical devices and blood damage prediction

Mauro Grigioni1, Giuseppe D'Avenio, Umberto Morbiducci

  • 1Department of Technology and Health, ISS, Rome, Italy.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
|January 24, 2009
PubMed

Insights

Cardiovascular device implantation can cause thromboembolic events and hemolysis. Analyzing device-specific fluid dynamics using techniques like LDA or PIV helps correlate hemodynamics with clinical outcomes and blood damage.

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Research
  • Fluid Dynamics

Background:

  • Cardiovascular device implantation, including prosthetic heart valves, is common but associated with complications.
  • Thromboembolic events and hemolysis are significant clinical problems following device implantation.

Purpose of the Study:

  • To analyze the relationship between the fluid dynamics of cardiovascular devices and clinical outcomes.
  • To investigate methods for correlating experimental findings with blood damage.

Main Methods:

  • Utilizing advanced techniques such as Laser Doppler Anemometry (LDA) and Particle Image Velocimetry (PIV).
  • Evaluating the local hemodynamical performance of implantable devices.

Main Results:

  • The study focuses on the analysis of fluid dynamics related to cardiovascular devices.
  • The correlation between experimental findings and blood damage remains a key area of investigation.

Conclusions:

  • Understanding device-specific fluid dynamics is crucial for predicting and mitigating clinical complications.
  • Advanced techniques like LDA and PIV are essential for assessing hemodynamical performance and inferring potential adverse clinical effects.

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