Monitoring of global cerebral ischemia using instantaneous phase variation plots

In this paper, the derivative of the instantaneous phase of electroencephalographic (EEG) signals is used as a basis for monitoring of global cerebral ischemia. Visual and quantitative results were obtained from six rodents that were subject to 3, 5 and 7 minutes of global ischemic brain injury by asphyxic cardiac arrest. Results show that the variations in the instantaneous phase are capable of amplifying the variations during the various stages of the recovery process and may serve as a novel analytical approach to grade and classify brain rhythms during global ischemic brain injury and recovery.