Related Experiment Video
Updated: Jun 26, 2026

Cell-Free Scaled Production and Adjuvant Addition to a Recombinant Major Outer Membrane Protein from Chlamydia muridarum for Vaccine Development
Published on: March 16, 2022
[Prediction of the B cell epitopes for the major outer membrane protein of Chlamydia trachomatis]
Shanli Zhu1, Zhaohui Shi, Pengfei Wang
1Department of Microbiology & Immunology, Wenzhou Medical College, Wenzhou 325000, China.
Abstract:
To predict the B cell epitopes for major outer membrane protein (MOMP) of Chlamydia trachomatis (CT), the secondary structure of CT MOMP was predicted by the methods of GOR based on the sequence of amino acids of E serotype CT MOMP. By combining the comprehensive analysis of transmembrane domain, hydrophilicity profile, surface probability, antigenic index and average flexibility, the B cell predominant epitopes of CT MOMP were further predicted. The N-terminal No. 73-81, 217-225, 377-386, 261-270 and 161-175 were the predominant B cell epitopes. Prediction of the B cell epitopes for the CT MOMP by the multi-parameters is helpful for the identification of B cell epitopes.
Related Concept Videos
Bacterial Phylum Chlamydiae
Outer Layers of the Cell Envelope
Protein Transport to the Outer Chloroplast Membrane
Two models describe the mechanism of precursor recognition and entry across the outer membrane through the TOC complex. Model 1 suggests the newly synthesized precursor binds to the TOC receptor 159 and forms a complex.
Bacterial Translocation and Protein Secretion
Protein Transport to the Inner Chloroplast Membrane

