Related Experiment Video
Updated: Jun 26, 2026

Analyzing and Building Nucleic Acid Structures with 3DNA
Published on: April 26, 2013
Conformational analysis (geometry optimization) of nucleosidic antitumor antibiotic showdomycin by Arguslab 4
Afshan Naz1, Khalida Bano, Farhat Bano
1Department of Biochemistry, University of Karachi, Karachi-75270, Pakistan.
Abstract:
Showdomycin is a naturally maleimide antitumor antibiotic of the C-nucleoside, it inhibits the nucleic acid synthesis in bacteria. Conformational analysis and geometry optimization of showdomycin was performed according to the Hartree-Fock (HF) calculation method by ArgusLab 4.0.1 software. The minimum potential energy is calculated by geometry convergence function by ArgusLab software. The most feasible position for the drug to interact with the receptor was found to be 0.269696 K.cal/mole.
More Related Videos
10:29Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
Published on: May 9, 2025
09:15Combining X-Ray Crystallography with Small Angle X-Ray Scattering to Model Unstructured Regions of Nsa1 from S. Cerevisiae
Published on: January 10, 2018
Related Concept Videos
Nucleic Acid Structure
DNA Structure
DNA has a double-helix structure. The...
Conformations of Cyclohexane
The chair form is the most stable and derives its name from its resemblance to the “easy chair.” In the chair conformation, two carbon atoms are arranged out-of-plane — one above and one below, minimizing the torsional strain. In the chair form, the bond angle is very close to the ideal tetrahedral value,...