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[Corneal manifestations in systemic diseases].

J Zarranz Ventura¹, E De Nova, J Moreno-Montañés

¹Departamento de oftalmología, Clínica Universitaria de Navarra, Pamplona 31008, Spain. jzarranz@unav.es

Anales Del Sistema Sanitario De Navarra

|January 27, 2009

Summary

Systemic diseases can manifest in the cornea, impacting vision. This review details prevalent corneal alterations linked to pulmonary, connective tissue, and dermatologic conditions, aiding clinical understanding.

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Area of Science:

Ophthalmology
Internal Medicine
Pathology

Context:

Corneal alterations are frequently associated with various systemic diseases.
Understanding these connections is crucial for comprehensive patient care.
A systematic review of prevalent systemic conditions affecting the cornea is warranted.

Purpose:

To categorize and describe the most prevalent and characteristic corneal manifestations of systemic diseases.
To provide a structured overview of pathologies affecting the cornea across different organ systems.

Summary:

This paper reviews corneal alterations associated with pulmonary, connective tissue (including collagen, rheumatologic, and idiopathic inflammatory diseases), dermatologic, cardiovascular, hematologic, digestive, and hepatopancreatic diseases.
It also covers endocrine, metabolic, malnutrition-related, otorhinolaryngologic, and genetic conditions impacting the cornea.
Ocular toxicity induced by drugs is also briefly addressed.

Impact:

Facilitates a more organized approach to diagnosing and managing corneal complications of systemic diseases.
Enhances clinical understanding of the diverse systemic origins of corneal pathology.
Serves as a valuable resource for ophthalmologists and internists managing patients with complex conditions.