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Updated: Jun 26, 2026

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
Published on: October 21, 2022
Cost of corneal transplantation for the Quebec health care system
Jean-Pascal F Roussy1, Marie-Josée Aubin, Isabelle Brunette
1Faculty of Pharmacy, University of Montreal, Montreal, Que.
Objective:
Although corneal graft is a common, long-standing procedure, little is known about its economic impact. The purpose of this study was to estimate resource use and costs associated with corneal transplantation according to a public third-party perspective.
Design:
Retrospective study using claim data from the Régie de l'assurance maladie du Québec (RAMQ).
Participants:
A total of 610 subjects were included in the study. Mean age was 54.8 (SD 20.4) years.
Methods:
The RAMQ provided medical and pharmaceutical data for a random sample of 75% of the patients who underwent a corneal graft procedure between June 1, 1999, and May 31, 2002. Resource usage data, defined as medical interventions, physician visits, and medication, were collected for a 3-year postoperative follow-up period. Hospital costs associated with corneal graft were obtained from the University of Montreal Hospital Centre costing system.
Results:
The average costs per patient for graft and anesthesia were $501 (SD $75) and $115 (SD $124), respectively. The mean cost per patient for physician visits was $276 (SD $146). The mean number of physician visits per patient during the follow-up was 14.9 (SD 9.1). The cost per patient for medication was $337 (SD $1075). The average total cost per patient was $1229 (SD $1125). Costs incurred by the hospital represented a total of $1942.
Conclusions:
The overall cost of corneal graft, including a 3-year follow-up, was estimated at $3171 ($1229 RAMQ, $1942 hospital). The majority of these costs occurred at the time of the procedure.
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