Related Experiment Video
Updated: Jun 26, 2026

05:16
Sleeve Gastrectomy in Mice using Surgical Clips
Published on: November 14, 2020
Laparoscopic sleeve gastrectomy versus intragastric balloon: a case-control study.
Alfredo Genco1, Massimiliano Cipriano, Alberto Materia
1Medical School, Paride Stefanini Surgical Department, La Sapienza University, Rome, Italy.
Surgical Endoscopy
|January 27, 2009
Summary
The BioEnterics intragastric balloon (BIB) is a better short-term option than laparoscopic sleeve gastrectomy (LSG) for initial weight loss. While both procedures aid weight loss, BIB shows fewer complications and better sustained results over 12 months.
Area of Science:
- Bariatric Surgery
- Gastroenterology
- Weight Management
Background:
- Obesity is a significant global health concern requiring effective weight loss strategies.
- Bariatric procedures are often employed for substantial and sustained weight reduction.
- Initial bariatric procedures aim to facilitate weight loss before more invasive surgeries.
Purpose of the Study:
- To compare the efficacy of laparoscopic sleeve gastrectomy (LSG) and BioEnterics intragastric balloon (BIB) for weight loss and comorbidity management.
- To evaluate these procedures as a first-step intervention over a 12-month follow-up period.
- To determine the suitability of LSG and BIB prior to more invasive bariatric surgery.
Main Methods:
- A comparative study involving 40 patients undergoing LSG and 80 patients receiving BIB therapy.
- Data collected included procedure time, hospital stay, complications, and weight loss parameters (BMI, %EWL, %EBL).
- Follow-up assessments were conducted at 6 and 12 months post-intervention.
Main Results:
- No mortality or major complications were reported in either the LSG or BIB groups.
- At 6 months, both groups showed similar BMI reductions.
- After 12 months, LSG patients continued to lose weight, while BIB patients experienced weight regain, despite dietary adherence. No significant differences in comorbidity reduction were observed between groups.
Conclusions:
- Both LSG and BIB are viable first-step procedures for initiating weight loss.
- LSG involves risks associated with general anesthesia and surgery, while BIB has a low rate of minor complications like psychological intolerance.
- Currently, BIB is considered a preferable short-term (12-month) first-step procedure compared to LSG due to its safety profile and ease of use.
