Related Experiment Video
Updated: Jun 26, 2026
Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model
Published on: May 21, 2013
[Matrix-augmented autologous chondrocyte implantation in the knee--arthroscopic technique]
Christoph Erggelet1, Johannes Holz, Andreas Lahm
1Department für Orthopädie und Traumatologie, Universitätsklinikum Freiburg, Freiburg. christoph.erggelet@uniklinik-freiburg.de
Objective:
Arthroscopic implantation of resorbable, three-dimensional scaffolds for the treatment of full-thickness cartilage defects.
Indications:
Full-thickness cartilage defect mainly in the knee joint.
Contraindications:
Advanced osteoarthritis, rheumatoid arthritis, avascular osteonecrosis.
Surgical Technique:
Debridement of the defect, assessment of the defect size, sizing of the implant, implantation into the joint, and fixation.
Postoperative Management:
Continuous active and passive motion, pain-adapted weight bearing with crutches, possibly toe-touch loading depending on size and localization of the defect.
Results:
After 2 years, good and excellent results in 80% of the cases with femoral cartilage defects on the modified Cincinnati Knee Rating Scale. Inferior results for defects of the patella and tibia.
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