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A membrane-free plethysmograph for recording volume changes including microlitres.
N Krishnamurthy1, S Bharathi, D P Thombre
1Department of Physiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry.
Indian Journal of Physiology and Pharmacology
|January 1, 1991
Summary
A novel plethysmography technique measures small volume changes without airtight chambers. This method accurately assesses experimental edema and human hand blood flow.
Area of Science:
- Physiology
- Medical Devices
- Biomedical Engineering
Background:
- Traditional plethysmography often requires airtight chambers, limiting its application.
- Measuring minute volume changes is crucial for understanding physiological processes.
Purpose of the Study:
- To describe a novel plethysmography method.
- To demonstrate its sensitivity for microlitre volume changes.
- To validate its use in physiological measurements.
Main Methods:
- Development of a plethysmography technique.
- Non-invasive measurement approach.
- Application in experimental edema and human hand blood flow studies.
Main Results:
- The method successfully measures microlitre volume changes.
- Effective application in experimental edema models.
- Accurate blood flow assessment in the human hand.
Conclusions:
- A new, non-chamber plethysmography method is presented.
- The technique is sensitive and versatile for physiological studies.
- Demonstrated utility in edema and blood flow research.