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An efficient carbene-catalyzed access to 3,4-dihydrocoumarins

Kirsten Zeitler1, Christopher A Rose

  • 1Institut für Organische Chemie, Universität Regensburg, D-93053 Regensburg, Germany. kirsten.zeitler@chemie.uni-regensburg.de

The Journal of Organic Chemistry
|January 28, 2009
PubMed
Summary

Dihydrocoumarins, important flavor and fragrance compounds, are efficiently synthesized from o-hydroxycinnamaldehydes using N-heterocyclic carbene catalysis. This method offers a mild and atom-economic route to these valuable molecules.

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