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Does ICD indication affect quality of life and levels of distress?
Susanne S Pedersen1, Samuel F Sears, Matthew M Burg
1Center of Research on Psychology in Somatic diseases, Tilburg University, The Netherlands. s.s.pedersen@uvt.nl
Insights
Implantable cardioverter defibrillators (ICDs) for primary prevention do not negatively impact quality of life or distress. Patients receiving an ICD for primary prophylaxis report similar outcomes to those receiving it for secondary prevention.
Area of Science:
- Cardiology
- Medical Devices
- Patient-Centered Outcomes Research
Background:
- Implantable cardioverter defibrillators (ICDs) are crucial for managing life-threatening arrhythmias.
- Recent expansion of ICD indications includes primary prophylaxis, raising questions about patient-centered outcomes.
- Debate exists regarding the impact of ICD implantation on quality of life (QoL) and patient distress.
Purpose of the Study:
- To examine the evidence on whether ICD indication (primary vs. secondary prophylaxis) affects patient-centered outcomes.
- To assess the impact of ICD therapy indication on QoL, anxiety, and depression.
Main Methods:
- A comprehensive literature search was performed on PubMed and Web of Science (2002-present).
- Studies focused on ICD indication and patient-centered outcomes, including QoL and psychological distress.
- Five studies (seven articles) meeting the criteria were identified and analyzed.
Main Results:
- No significant effect of ICD indication on patient-centered outcomes was reported across the included studies.
- No evidence suggests poorer QoL or increased distress in patients receiving ICDs for primary prophylaxis compared to secondary prophylaxis.
- Study sample sizes ranged from 91-426 patients, with prospective designs and 2-12 month follow-up periods.
Conclusions:
- Current evidence does not support a negative impact on QoL or distress based on ICD indication.
- This finding can aid cardiologists in clinical decision-making and patient counseling regarding ICD implantation.
- Further research may explore long-term effects and specific patient subgroups.
Abstract:
The implantable cardioverter defibrillator (ICD) is the treatment of choice for life-threatening arrhythmias, with ICD indications having recently been extended to include primary prophylaxis. Despite the medical benefits of the ICD, there is an ongoing debate as to the impact of the ICD on patients' lives, particularly whether primary prophylaxis implantation may impact adversely on patient-centered outcomes such as quality of life (QoL) and distress. We examined the evidence for a role of ICD indication on these patient-centered outcomes. A literature search was conducted on PubMed and Web of Science from 2002 to present, focusing on indication for ICD therapy and patient-centered outcomes (i.e., anxiety, depression, disease-specific, or general QoL). We identified five studies (seven articles) concerning the impact of indication on patient-centered outcomes. Sample sizes varied from 91-426 patients across studies, five of seven articles used a prospective design, and follow-up ranged from 2-12 months. No study reported an effect for indication on patient-centered outcomes. There is no evidence to suggest that patients receiving an ICD for primary prophylaxis have subsequent poorer QoL and greater distress than patients receiving an ICD for secondary prophylaxis. This knowledge may help cardiologists in the clinical management of patients, in particular when discussing ICD implantation with patients.
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