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[Pyoderma gangrenosum with aseptic spleen abscess].

N Brahimi¹, E Maubec, O Boccara

¹Service de dermatologie, hôpital Bichat, Assistance publique-Hôpitaux de Paris, université Paris-VII Denis-Diderot, 46, rue Henri-Huchard, 75877 Paris cedex 18, France.

Annales De Dermatologie Et De Venereologie

|January 28, 2009

Summary

Pyoderma gangrenosum rarely affects internal organs. This case highlights splenic involvement, mimicking infection, emphasizing the need for screening for associated hematologic malignancies.

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Area of Science:

Dermatology
Internal Medicine
Pathology

Background:

Pyoderma gangrenosum (PG) is a neutrophilic dermatosis.
Systemic involvement in PG is uncommon.
PG can be associated with underlying systemic diseases.

Observation:

A 68-year-old male with pustular PG and multiple myeloma presented with abdominal pain.
Imaging revealed a splenic abscess.
Histopathology showed leukocytic infiltration, with negative cultures.

Findings:

The patient was diagnosed with splenic involvement of pyoderma gangrenosum.
Treatment with systemic corticosteroids was successful.
Hematological status remained stable.

Implications:

Splenic involvement in PG is rare and can be misdiagnosed as infection.
Routine screening for systemic diseases, especially hematologic malignancies, is crucial in PG cases.
This case underscores the importance of a comprehensive diagnostic approach for pyoderma gangrenosum.