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Updated: Jun 26, 2026

Translating Ribosome Affinity Purification (TRAP) to Investigate Arabidopsis thaliana Root Development at a Cell Type-Specific Scale
Published on: May 14, 2020
The gene regulatory network for root epidermal cell-type pattern formation in Arabidopsis
John Schiefelbein1, Su-Hwan Kwak, Yana Wieckowski
1Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, 48109, USA. schiefel@umich.edu
Abstract:
A fundamental aspect of multicellular development is the patterning of distinct cell types in appropriate locations. In this review, the molecular genetic control of cell-type pattern formation in the root epidermis of Arabidopsis thaliana is summarized. This developmental system represents a simple and genetically tractable example of plant cell patterning. The distribution of the two epidermal cell types, root-hair cells and non-hair cells, are generated by a combination of positional signalling and lateral inhibition mechanisms. In addition, recent evidence suggests that reinforcing mechanisms are used to ensure that the initial cell fate choice is adopted in a robust manner.
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