Related Experiment Video
Updated: Jun 26, 2026

A Preclinical Model of Exertional Heat Stroke in Mice
Published on: July 1, 2021
[Heat stroke and burns resulting from use of sauna]
Kim Rünitz1, Tom Hartvig Jensen
1Intensiv Afdeling 4131, Rigshospitalet, DK-2100 København Ø. kimrunitz@gmail.com
Abstract:
We describe a case of severe heat stroke resulting from exposure to extreme heat in a sauna for an unknown period of time. The patient sustained 20% 2nd degree burns. On arrival at the emergency department, the patient's temperature was 40.5 degrees C. At the critical care unit, the patient developed severe multi-organ failure and critical polyneuropathy. Severe heat stroke is a rare diagnosis in Denmark. The treatment is symptomatic and the prognosis is grave, especially in combination with severe burns.
Related Concept Videos
Homeostatic Imbalances in Body Temperature
Increased Body Temperature
Burn Injuries
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Mechanisms of Heat Transfer
Conduction, accounting for approximately 3% of body heat loss at rest, is the process of exchanging heat between molecules of two materials in direct contact. This can result in both heat loss and gain. For instance, when the body is submerged in water, which conducts heat 20 times more effectively than air, it can either lose or gain significant heat.
Body Temperature
Body Temperature
The average body temperature is approximately 37°C (98.6°F) and typically ranges from 36.1–37.2°C (97–99°F), remaining relatively stable...

