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Maxillary sinus grafting with a nano-structured biomaterial: preliminary clinical and histological results
S Stübinger1, S Ghanaati, C Orth
1Department for Oral, Cranio-Maxillofacial and Facial Plastic Surgery, Medical Center of Johann Wolfgang Goethe University Frankfurt, Frankfurt am Main, Germany. sstuebinger@uhbs.ch
Background:
In this study the potential of a new and entirely synthetic, nano-structured hydroxyapatite-based biomaterial for sinus floor augmentation is evaluated.
Methods:
20 sinus floor elevations were carried out in a total of 20 patients. After a healing period of 6 months, in 10 cases cylinder-shaped bone biopsies were taken from the augmented maxillary region using trephine burs.
Results:
The healing period progressed without any complications. General and specific histological analysis of the bone biopsies showed a high osteoclast activity at the margin of the biomaterial which was well integrated into the newly formed bone.
Conclusion:
This study demonstrates that new trabecular bone is formed after grafting with the nanocrystalline bone substitute after 6 months. Ongoing histomorphological studies are necessary to quantify the biomaterial-bone ratio and the exact amount of newly built bone in the augmented cavity after 6 months.
