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Published on: August 14, 2019
Three new flavonol triglycosides from Derris trifoliata
Lu-Rong Xu1, Pei Zhou, Yue-E Zhi
1School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Journal of Asian Natural Products Research
|January 30, 2009
Summary
Three new flavonol triglycosides were identified in Derris trifoliata, alongside two known compounds. These findings expand our understanding of the chemical constituents in this plant species.
Area of Science:
- Phytochemistry
- Natural Product Chemistry
Background:
- Derris trifoliata is a plant species known for its diverse phytochemical profile.
- Flavonol glycosides are a class of natural compounds with potential biological activities.
Purpose of the Study:
- To isolate and characterize novel and known flavonol glycosides from the aerial parts of Derris trifoliata.
- To contribute to the phytochemical knowledge of the Derris genus.
Main Methods:
- Extraction of compounds from the aerial parts of Derris trifoliata.
- Isolation and purification of flavonol triglycosides and glycosides using chromatographic techniques.
- Structure elucidation employing comprehensive chemical and spectroscopic analyses (e.g., NMR, Mass Spectrometry).
Main Results:
- Isolation of three new flavonol triglycosides: kaempferol-3-O-alpha-L-rhamnopyranosyl-(1 --> 6)-beta-D-glucopyranosyl-(1 --> 3)-beta-D-glucopyranoside (1), quercetin-3-O-alpha-L-rhamnopyranosyl-(1 --> 6)-beta-D-glucopyranosyl-(1 --> 3)-beta-D-glucopyranoside (2), and quercetin-3-O-alpha-L-rhamnopyranosyl-(1 --> 6)-beta-D-glucopyranosyl-(1 --> 2)-beta-D-glucopyranoside (3).
- Identification of two known flavonol glycosides: kaempferol-3-O-alpha-L-rhamnopyranosyl-(1 --> 6)-beta-D-glucopyranoside and kaempferol-3-O-alpha-L-rhamnopyranosyl-(1 --> 6)-beta-D-glucopyranosyl-(1 --> 2)-beta-D-glucopyranoside.
- Confirmation of structures through detailed chemical and spectroscopic data analysis.
Conclusions:
- The study successfully identified and characterized five flavonol glycosides from Derris trifoliata, including three novel compounds.
- The findings enhance the understanding of the chemical diversity within the Derris genus and provide a basis for further research into the biological activities of these compounds.
