Intertriginous pustular psoriasis

Jane S Bellet1, Sarah L Chamlin, Albert C Yan

  • 1Departments of Dermatology and Pediatrics at Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA.

Insights

Infantile pustular psoriasis, often misdiagnosed, presents as neck rashes. This condition may indicate widespread psoriasis development later in life.

Area of Science:

  • Dermatology
  • Pediatrics

Background:

  • Infantile pustular psoriasis is a rare condition.
  • It often presents as erythematous papules or pustules on the neck and intertriginous areas.

Observation:

  • Six infant cases are described, with initial misdiagnoses including dermatitis or infections.
  • Biopsy confirmed pustular psoriasis in five of six infants.

Findings:

  • Psoriasis became widespread in four cases over time.
  • Treatment involved topical and systemic therapies, with some cases being recalcitrant.

Implications:

  • Pustular psoriasis should be considered in infants with intertriginous papulopustular eruptions.
  • Infantile-onset intertriginous pustular psoriasis may predict future widespread disease.

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