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Updated: Jun 26, 2026

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. II. Total Culturable Virus Assay
Published on: September 11, 2016
[When an enterovirus emerges]
B Kairis1, P Sauter, A Goffard
1Laboratoire de Virologie/UPRES EA3610, Faculté de Médecine, Centre de Biologie Pathologie, Université Lille-2, CHRU de Lille, Bâtiment P.- Boulanger, Boulevard du Pr-Jules-Leclercq, 59037 Lille, France.
Abstract:
Most of enterovirus infections are benign and the rate of mortality is low in countries with temperate climates. But since the late 1990s, Enterovirus 71 (EV-71) has become much more aggressive in Asian countries, with the outcome of a neurogenic pulmonary oedema syndrome and it is responsible for huge epidemics. The virological diagnosis rely upon viral isolation and identification by sero-neutralization, and upon the detection of specific IgM by ELISA and viral RNA by RT-PCR. There is no specific treatment to fight this virus, but innovative strategies, especially based on interfering RNA, are under investigation.
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