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Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
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Related Experiment Video

Updated: Jun 26, 2026

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. II. Total Culturable Virus Assay
11:09

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. II. Total Culturable Virus Assay

Published on: September 11, 2016

[When an enterovirus emerges].

B Kairis1, P Sauter, A Goffard

  • 1Laboratoire de Virologie/UPRES EA3610, Faculté de Médecine, Centre de Biologie Pathologie, Université Lille-2, CHRU de Lille, Bâtiment P.- Boulanger, Boulevard du Pr-Jules-Leclercq, 59037 Lille, France.

Pathologie-Biologie
|January 31, 2009
PubMed
Summary
This summary is machine-generated.

Enterovirus 71 (EV-71) infections have become aggressive in Asia, causing severe neurogenic pulmonary edema. Current diagnostics include viral isolation and RNA detection, with RNA interference therapies under investigation.

More Related Videos

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. I. Collection of Virus Samples
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EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. Part III. Virus Detection by RT-qPCR
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EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. Part III. Virus Detection by RT-qPCR

Published on: January 16, 2016

Related Experiment Videos

Last Updated: Jun 26, 2026

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. II. Total Culturable Virus Assay
11:09

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. II. Total Culturable Virus Assay

Published on: September 11, 2016

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. I. Collection of Virus Samples
10:48

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. I. Collection of Virus Samples

Published on: March 28, 2015

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. Part III. Virus Detection by RT-qPCR
12:32

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. Part III. Virus Detection by RT-qPCR

Published on: January 16, 2016

Area of Science:

  • Virology
  • Infectious Diseases
  • Public Health

Context:

  • Enterovirus infections are typically benign in temperate climates.
  • Since the late 1990s, Enterovirus 71 (EV-71) has emerged as a significant threat in Asian countries.
  • EV-71 outbreaks are associated with severe neurogenic pulmonary edema syndrome.

Purpose:

  • To summarize the current understanding of Enterovirus 71 (EV-71) epidemiology and clinical presentation.
  • To outline the diagnostic methods for EV-71 infections.
  • To review potential therapeutic strategies for EV-71.

Summary:

  • EV-71, once benign, now causes severe epidemics in Asia, characterized by neurogenic pulmonary edema.
  • Virological diagnosis involves viral isolation, sero-neutralization, IgM detection via ELISA, and viral RNA detection via RT-PCR.
  • No specific antiviral treatment exists, but RNA interference strategies are being explored.

Impact:

  • Highlights the changing epidemiology of EV-71 and its severe clinical outcomes.
  • Underscores the importance of accurate and timely diagnosis for managing EV-71 outbreaks.
  • Emphasizes the urgent need for effective treatments against this emerging viral pathogen.