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Updated: Jun 26, 2026

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
Indications for coronary artery bypass grafting in 2009: what is left to surgery
D J Caparrelli1, M Ghazoul, E B Diethrich
1The Arizona Heart Institute, Phoenix, AZ 85006, USA. dcaparrelli@azheart.com
Insights
Coronary artery bypass grafting (CABG) offers significant benefits for specific patients with complex coronary artery disease, especially those with diabetes or left ventricular dysfunction. Ongoing research is crucial as treatments evolve.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
Background:
- Coronary artery bypass grafting (CABG) is a common cardiac surgery.
- The field of coronary intervention is rapidly evolving with new technologies and research.
- Comparing surgical versus percutaneous revascularization is complex due to patient variability and treatment advancements.
Purpose of the Study:
- To outline current indications for surgical revascularization (CABG).
- To provide an understanding of CABG's role in managing coronary artery disease.
- To acknowledge the need for ongoing re-evaluation of recommendations.
Main Methods:
- Review of available literature on CABG and percutaneous coronary intervention.
- Analysis of patient populations benefiting from surgical revascularization.
- Consideration of comorbid conditions and disease severity.
Main Results:
- CABG provides significant benefits in specific patient groups.
- Patients with diabetes, left ventricular dysfunction, left main disease, or three-vessel disease often benefit from CABG.
- Improvements in percutaneous therapies and medical management complicate direct comparisons.
Conclusions:
- Surgical revascularization remains crucial for select patients with coronary artery disease.
- The indications for CABG are influenced by patient comorbidities and disease extent.
- Continuous study and re-evaluation are necessary due to the dynamic nature of cardiovascular interventions.
Abstract:
Coronary artery bypass grafting (CABG) remains the most common procedure performed by cardiac surgeons, yet it is clear that the landscape of coronary intervention is constantly changing as new technology is introduced and data from countless studies continues to be published. However, no single study will be able to clearly define the indications for surgical versus percutaneous revascularization in every clinical scenario given the complexity of this disease as well as that of the patients it afflicts. Moreover, the significant improvements in percutaneous therapy, medical therapy management, perioperative care and secondary prevention after revascularization have decreased the morbidity and mortality of coronary artery disease making comparison between therapies far more difficult. Based on the available literature to date, surgical revascularization (CABG) provides significant benefit in certain patient populations; particularly those with comorbid conditions (for example diabetes, left ventricular [LV] dysfunction) and with more severe disease (for example left main, three-vessel). The goal of this article is to outline the current for surgical revascularization (CABG) understanding that coronary artery disease will continue be an important cause of morbidity and mortality and further study and re-evaluation of these recommendations will likely be necessary as time goes on.
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