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Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...

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Related Experiment Videos

Multifocal skeletal tuberculosis in children.

M A Rahman1, M Mutanabbi, M H Rahman

  • 1Department of Pediatrics, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh. atiar777@yahoo.com

Mymensingh Medical Journal : MMJ
|February 3, 2009
PubMed
Summary
This summary is machine-generated.

This case report details a rare instance of multifocal bone tuberculosis in a child. Early diagnosis and a comprehensive anti-tubercular regimen led to successful treatment.

Related Experiment Videos

Area of Science:

  • Pediatric Infectious Diseases
  • Skeletal Tuberculosis
  • Mycobacterium tuberculosis Infections

Background:

  • Tuberculosis (TB) can present with multifocal bone involvement, though rare, particularly in endemic regions.
  • Pediatric skeletal TB requires high clinical suspicion for timely diagnosis and management.
  • Disseminated TB can affect multiple bones, posing diagnostic challenges.

Observation:

  • A 3-year-old boy presented with gait disturbance, low-grade fever, and swelling in multiple joints and limbs.
  • Diagnostic workup revealed positive Mantoux test, elevated ESR, hilar lymphadenopathy, spinal deformities with paravertebral collection, and multiple lytic bone lesions.
  • Bone marrow aspirate culture confirmed Mycobacterium tuberculosis, and ultrasonography identified a psoas abscess.

Findings:

  • The patient exhibited extensive skeletal involvement indicative of multifocal bone tuberculosis.
  • Diagnostic imaging demonstrated characteristic lytic lesions with periosteal reaction and cortical thickening in long bones and spine.
  • Microbiological confirmation of Mycobacterium tuberculosis from bone marrow aspirate was crucial for diagnosis.

Implications:

  • This case highlights the importance of considering multifocal bone TB in children with suggestive symptoms and endemic exposure.
  • Prompt and appropriate anti-tubercular therapy, including a multi-drug regimen, is essential for favorable outcomes.
  • Aggressive management involving surgical intervention for abscesses may be necessary in complex cases.