Related Experiment Video
Updated: Jun 26, 2026

A Modified Trier Social Stress Test for Vulnerable Mexican American Adolescents
Published on: July 10, 2017
Retention and protocol adherence of Hispanic volunteers in a longitudinal trial
Elaine L Larson1, Yu-Hui Ferng, Jennifer Wong-McLoughlin
1School of Nursing, Columbia University, New York, NY 10032, USA. ELL23@columbia.edu
Objectives:
To compare Hispanic research volunteers with high and low levels of study retention and adherence.
Methods:
Correlational analysis of demographics, recruitment strategies, knowledge, and attitudes of 470 households in a clinical trial.
Results:
Within 12 months, 53 (11.3%) households dropped out; those less certain about some factual information were more likely to drop out (P < 0.05). Participants born outside the United States were more likely to adhere to protocols (P = 0.03). Flyers were effective for recruiting only 3% of participants.
Conclusions:
In newly immigrated populations, written recruitment materials may be ineffective; knowledge and attitudes may be important for study retention and adherence.
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