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True osseous metaplasia of the endometrium: the bone is not from a fetus
Enrique Cayuela1, Tirso Perez-Medina, Joan Vilanova
1Obstetrics and Gynecology Department, Hospital General Hospitalet, Barcelona, Spain.
Objective:
To identify the origin of calcified tissue in endometrial ossification.
Design:
DNA analyses from the ossified tissue and from the woman were studied to compare both genotypes.
Setting:
University and general hospitals.
Patient(S):
A 27-year-old infertile woman diagnosed of osseous metaplasia of the endometrium.
Intervention(S):
Hysteroscopic resection of the endometrial osseous metaplasia for DNA analysis.
Main Outcome Measure(S):
DNA comparison between the patient and the osseous tissue extracted from the uterus.
Result(S):
All markers produced the same allele length for both blood and endometrial biopsy (including bones), thus confirming the same genetic origin.
Conclusion(S):
Endometrial ossification is derived from the patient, resulting in a true osseous metaplasia.
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