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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

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Published on: July 11, 2013

Topical tar: back to the future.

Kapila V Paghdal1, Robert A Schwartz

  • 1Dermatology and Pathology, New Jersey Medical School, Newark, New Jersey 07103, USA.

Journal of the American Academy of Dermatology
|February 3, 2009
PubMed
Summary
This summary is machine-generated.

Medicinal tar, including coal and wood tars, effectively treats chronic skin conditions like psoriasis and dermatitis. Despite historical use and odor concerns, tar preparations offer lesion clearing and prolonged remission with topical application.

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Area of Science:

  • Dermatology
  • Pharmacology
  • Toxicology

Background:

  • Medicinal tar has a long history in treating skin disorders.
  • Coal tar and wood tars are utilized for various dermatologic conditions.
  • Tar preparations have undergone modifications to improve patient acceptability.

Purpose of the Study:

  • To review the pharmacology of medicinal tars.
  • To discuss formulations, efficacy, and adverse effects of tar preparations.
  • To examine the use of crude coal tar and other tars in dermatology.

Main Methods:

  • Review of historical and modern dermatologic literature.
  • Analysis of occupational and epidemiological studies on tar.
  • Evaluation of tar formulations and their clinical application.

Main Results:

  • Tar is effective for chronic stable plaque psoriasis, scalp psoriasis, atopic dermatitis, and seborrheic dermatitis.
  • Combination therapy with tar, medications, or phototherapy enhances treatment outcomes.
  • Topical tar use has not been confirmed as carcinogenic in epidemiological studies, despite occupational risks.

Conclusions:

  • Tar remains a valuable treatment option for specific dermatologic conditions.
  • Modifications have improved tar's tolerability and patient compliance.
  • Tar therapy can achieve lesion clearance and extended remission periods.