Polypoid Acral Amelanotic Melanoma: A Rare Variant Treated with Wide and Deep Surgical Excision

Polypoid melanomas are unusual, as are amelanotic ones. Similarly, polypoid melanomas are not usually acral or amelanotic. They can be challenging to diagnose clinically, as they may resemble acral lentiginous nevus, polypoid Spitz nevus, eccrine poroma, schwannoma, pyogenic granuloma, verrucous carcinoma, fibrosarcoma, basal cell carcinoma, and pyoderma gangrenosum. We delineate a 64-year-old woman with an acral amelanotic polypoid melanoma on her sole. It was successfully removed surgically without limb amputation.