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Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts
Published on: December 22, 2015
[Clinical research of craniofacial bone autograft using mandibular outer cortex]
Yan-feng Zhao1, Xiao-jing Liu, Ping Lu
1Dept. of Oral and Maxillofacial Surgery, Dalian City Central Hospital, Dalian 116033, China.
Summary
Mandibular outer cortex bone grafts show varied resorption rates at different facial sites. Mandible sites experienced greater bone loss (20.8%) than maxilla sites (11.2%) after six months.
Area of Science:
- Oral and Maxillofacial Surgery
- Regenerative Medicine
- Biomaterials Science
Background:
- Autologous bone grafting is crucial for craniofacial reconstruction.
- Understanding graft volumetric stability is essential for predictable outcomes.
- Mandibular outer cortex is a potential source for onlay bone grafts.
Purpose of the Study:
- To evaluate volume changes of mandibular outer cortex grafts.
- To compare resorption rates at different craniofacial recipient sites.
- To identify factors influencing graft stability.
Main Methods:
- Six patients received simultaneous onlay bone grafts (mandibular outer cortex) to the mandible and malar regions.
- Three-dimensional computed tomography (3D-CT) scans were acquired immediately post-op and at 6 months.
- Graft volume changes were analyzed using 3D-CT based true-up and dissection techniques.
Main Results:
- Significant bone resorption was observed in all grafts after 6 months.
- Mandibular recipient sites showed higher resorption rates (20.8% ± 7.2%) compared to anterior maxilla sites (11.2% ± 2.3%).
- Resorption was most prominent at the inferior and posterior borders of the mandible.
Conclusions:
- Bone resorption of mandibular outer cortex onlay grafts varies significantly with recipient site.
- Differences in the mechanical environment at recipient sites likely influence resorption rates.
- Quantifying resorption rates aids in optimizing clinical application of these grafts.
