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Updated: Aug 14, 2026

04:11
The Establishment of a Murine Maxillary Orthodontic Model
Published on: October 27, 2023
[Maxillomandibular advancement]
1-övertandläkare, -specialist i käkkirurgi, Karolinska universitetssjukhuset, Stockholm.
Summary
Maxillomandibular advancement (MMA) surgery effectively treats obstructive sleep apnea (OSA) by increasing airway volume. Despite its proven benefits and guideline recommendations, MMA remains underutilized, necessitating greater awareness and implementation.
Area of Science:
- Sleep Medicine
- Otolaryngology
- Maxillofacial Surgery
Background:
- Obstructive sleep apnea (OSA) is a prevalent disorder linked to serious health risks.
- Current treatments like CPAP may have compliance issues or insufficient efficacy.
- Surgical options are crucial for non-compliant or non-responsive OSA patients.
Purpose of the Study:
- To highlight the effectiveness of maxillomandibular advancement (MMA) for obstructive sleep apnea (OSA).
- To underscore the underutilization of MMA in Sweden despite its established benefits.
- To advocate for increased awareness and clinical implementation of MMA.
Main Methods:
- Review of existing meta-analyses and long-term studies on MMA efficacy.
- Presentation of two illustrative clinical cases of MMA for OSA.
- Analysis of guideline recommendations and current clinical practice in Sweden.
Main Results:
- MMA significantly reduces the apnea-hypopnea index (AHI) by over 50%.
- The procedure leads to normalized sleep parameters, improved quality of life, and high patient satisfaction.
- MMA is recognized in international and Swedish national recommendations but remains underutilized.
Conclusions:
- Maxillomandibular advancement (MMA) is a highly effective surgical treatment for obstructive sleep apnea (OSA).
- Increased awareness, national coordination, and broader clinical implementation are needed to improve OSA management with MMA.
- Addressing the underutilization of MMA can enhance patient outcomes and quality of life.

