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Changes in inflammatory mediators in peri-implant fluid after implant insertion
Mario Venza1, Maria Visalli, Giuseppe Lo Giudice
1Department of Odontostomatology, University of Messina, Messina, Italy.
Journal of Periodontology
|February 4, 2009
Summary
Submerged dental implants showed increased bone loss and periodontal issues compared to non-submerged implants over three years. This difference was linked to higher inflammatory markers in peri-implant fluid for submerged implants.
Area of Science:
- Dental Implantology
- Periodontology
- Biomaterials Science
Background:
- Endosseous dental titanium implants are crucial in modern restorative dentistry.
- Understanding implant placement techniques is vital for long-term patient care and periodontal health.
Purpose of the Study:
- To compare the influence of submerged versus non-submerged titanium implant placement on periodontal health.
- To evaluate clinical and biochemical markers of periodontal inflammation around implants.
Main Methods:
- Longitudinal study comparing submerged and non-submerged titanium implants.
- Assessment of plaque index (PI), gingival index (GI), probing depth (PD), clinical attachment level (CAL), and bone level.
- Measurement of histamine and arachidonic acid metabolites in peri-implant crevicular fluid over 36 months.
Main Results:
- Submerged implants showed significantly higher bone loss at 3 years (P <0.01).
- Clinical parameters (PI, GI, PD, CAL) were significantly worse for submerged implants at 24 and 36 months (P <0.05).
- Elevated histamine and reduced 15(S)-hydroxy-5,8,11,13-eicosatetraenoic acid in peri-implant fluid correlated with poor periodontal indices in the submerged group (P <0.001).
Conclusions:
- Submerged dental implants pose greater risks for periodontal complications than non-submerged implants.
- Variations in peri-implant crevicular fluid inflammatory mediators indicate increased risk with submerged implants.
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