Anesthetic considerations for major burn injury in pediatric patients

Gennadiy Fuzaylov1, Christina W Fidkowski

  • 1Department of Anesthesia and Critical Care, Pediatric Anesthesia Service, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. gfuzaylov@partners.org

Paediatric Anaesthesia
|February 4, 2009
PubMed

Insights

Pediatric patients with severe burn injuries present unique anesthetic challenges. Anesthesia providers must understand the physiological changes and implications for safe patient care.

Area of Science:

  • Pediatric Anesthesiology
  • Burn Critical Care

Background:

  • Major burn injury is a leading cause of death and disability in children.
  • Advances in burn care have increased survival rates for severe burn injuries.
  • Anesthesia providers are integral to the multidisciplinary care of critically ill pediatric burn patients.

Purpose of the Study:

  • To outline the anesthetic challenges associated with severe burn injury in pediatric patients.
  • To highlight the importance of understanding physiological derangements for anesthesia providers.
  • To inform anesthetic management strategies for pediatric burn victims.

Main Methods:

  • Review of physiological alterations in pediatric burn patients.
  • Analysis of anesthetic implications based on burn pathophysiology.
  • Discussion of specific challenges including airway management, vascular access, and hemodynamic instability.

Main Results:

  • Pediatric burn patients exhibit significant physiological changes impacting anesthesia.
  • Challenges include difficult airways, vascular access, fluid/electrolyte imbalances, and temperature dysregulation.
  • Increased requirements for muscle relaxants and opioids are common.

Conclusions:

  • Anesthesia providers face complex challenges in managing pediatric burn patients.
  • A thorough understanding of burn physiology is crucial for optimizing anesthetic care.
  • Multidisciplinary collaboration is essential for improving outcomes in pediatric burn survivors.

Related Concept Videos

Inhalational Anesthetics: Overview01:20

Inhalational Anesthetics: Overview

Inhalation anesthetics are drugs that induce general anesthesia upon inhalation. They work by increasing the sensitivity of GABAA receptors or inhibiting NMDA receptors, leading to a decrease in central nervous system activity. The depth of anesthesia can be rapidly adjusted by changing the concentration of the inhaled gas. Some common examples of inhalational anesthetics include volatile liquids like isoflurane, desflurane, sevoflurane and gases like xenon and nitrous oxide. Isoflurane, a...
Parenteral Anesthetics: Overview01:24

Parenteral Anesthetics: Overview

Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
Burn Injuries01:22

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
General Anesthesia: Overview01:24

General Anesthesia: Overview

Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Local Anesthetics: Common Agents and Their Applications01:23

Local Anesthetics: Common Agents and Their Applications

Local anesthetics (LAs) are commonly used for various applications in medical and dental procedures. Some of the common agents used are cocaine, lidocaine, and bupivacaine.
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...