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Updated: Jun 25, 2026

Preparation of Highly Porous Coordination Polymer Coatings on Macroporous Polymer Monoliths for Enhanced Enrichment of Phosphopeptides
Published on: July 14, 2015
TiO(2)-modified macroporous silica foams for advanced enrichment of multi-phosphorylated peptides
Jingjing Wan1, Kun Qian, Liang Qiao
1Department of Chemistry and Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials and Institute of Biomedical Sciences, Fudan University, Shanghai 200433, PR China.
Abstract:
Enriching peptides: Novel TiO(2)-modified macroporous materials (Ti-MOSF, see figure) have been synthesized with high surface area, large pore volume, and functional surfaces that are rich in coordinatively unsaturated Ti(IV) species, which can be applied in the specific extraction of phosphopeptides and which show a preferential capture of multi-phosphorylated peptides with low detection limits and high selectivity.

