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Updated: Jun 25, 2026
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Using a GFP-tagged TMEM184A Construct for Confirmation of Heparin Receptor Identity
Published on: February 17, 2017
Pattern-based recognition of heparin contaminants by an array of self-assembling fluorescent receptors
Richard B C Jagt1, Rodolfo F Gómez-Biagi, Mark Nitz
1Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON, M5S 3H6, Canada.
Angewandte Chemie (International Ed. in English)
|February 5, 2009
Abstract:
Tracking down potential killers: Strong host-guest interactions enable the facile combination of polycationic cyclodextrin binding motifs (blue) with fluorescent reporters (orange) tethered to a hydrophobic guest molecule (dark green). An array of supramolecular fluorescent receptors prepared by this modular approach was used for the pattern-based recognition of negatively charged contaminants in the anticoagulant drug heparin.
