Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Applications Of NMR In Biology01:25

Applications Of NMR In Biology

Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
The...
Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
In-situ Hybridization02:31

In-situ Hybridization

In situ hybridization (ISH) is a technique used to detect and localize specific DNA or RNA molecules in cells, tissue, or tissue sections using a labeled probe. The technique was first used in 1969 for the investigation of nucleic acids. It is currently an essential tool in scientific research and clinical settings, especially for diagnostic purposes.
Types of probes and labels
A probe is a complementary strand of DNA or RNA that binds to corresponding nucleotide sequences in a cell. Many...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Granzyme B PET Imaging Uncovers Dynamic Patterns of Disease Activity and Therapeutic Response in a Murine Colitis Model.

International journal of molecular sciences·2026
Same author

Authorship order in surgical research: Clarifying the role of middle authors.

The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·2026
Same author

Perforated Meckel's Diverticulum in a Neonate With Bucket-Handle Anorectal Malformation: A Rare Surgical Emergency.

Case reports in pediatrics·2026
Same author

Diagnostic Performance of PSMA PET/MRI in Characterizing LI-RADS 3 Observations in Patients with Cirrhosis.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2025
Same author

Developing a theranostic nanobody targeting FAP for cancer imaging and therapy.

EJNMMI radiopharmacy and chemistry·2025
Same author

Prognostic value of serological and PET/CT response kinetics in patients with multiple myeloma treated with BCMA CAR-T.

Leukemia·2025
Same journal

Machine Learning in PET: from Photon Detection to Quantitative Image Reconstruction.

Proceedings of the IEEE. Institute of Electrical and Electronics Engineers·2023
Same journal

Vector Symbolic Architectures as a Computing Framework for Emerging Hardware.

Proceedings of the IEEE. Institute of Electrical and Electronics Engineers·2023
Same journal

Unlocking the Emotional World of Visual Media: An Overview of the Science, Research, and Impact of Understanding Emotion: Drawing Insights From Psychology, Engineering, and the Arts, This Article Provides a Comprehensive Overview of the Field of Emotion Analysis in Visual Media and Discusses the Latest Research, Systems, Challenges, Ethical Implications, and Potential Impact of Artificial Emotional Intelligence on Society.

Proceedings of the IEEE. Institute of Electrical and Electronics Engineers·2023
Same journal

A review of deep learning in medical imaging: Imaging traits, technology trends, case studies with progress highlights, and future promises.

Proceedings of the IEEE. Institute of Electrical and Electronics Engineers·2023
Same journal

Synthetic Morphogenesis: introducing IEEE journal readers to programming living mammalian cells to make structures.

Proceedings of the IEEE. Institute of Electrical and Electronics Engineers·2023
Same journal

Robotic Assistance for Intraocular Microsurgery: Challenges and Perspectives.

Proceedings of the IEEE. Institute of Electrical and Electronics Engineers·2023
See all related articles

Related Experiment Video

Updated: Jun 25, 2026

MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent
06:54

MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent

Published on: September 3, 2013

Molecular MR Imaging Probes.

Umar Mahmood1, Lee Josephson

  • 1The authors are with the Center for Molecular Imaging Research, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129 USA.

Proceedings of the IEEE. Institute of Electrical and Electronics Engineers
|February 6, 2009
PubMed
Summary
This summary is machine-generated.

Magnetic resonance imaging (MRI) advances molecular imaging. This review highlights progress in multimodal agents, receptor, apoptosis, and angiogenesis imaging, plus cell tracking and gene imaging.

More Related Videos

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

Monitoring Dendritic Cell Migration using 19F / 1H Magnetic Resonance Imaging
08:12

Monitoring Dendritic Cell Migration using 19F / 1H Magnetic Resonance Imaging

Published on: March 20, 2013

Related Experiment Videos

Last Updated: Jun 25, 2026

MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent
06:54

MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent

Published on: September 3, 2013

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

Monitoring Dendritic Cell Migration using 19F / 1H Magnetic Resonance Imaging
08:12

Monitoring Dendritic Cell Migration using 19F / 1H Magnetic Resonance Imaging

Published on: March 20, 2013

Area of Science:

  • Medical Imaging
  • Molecular Biology
  • Biotechnology

Background:

  • Magnetic resonance imaging (MRI) is a powerful tool with broad applications in molecular imaging.
  • Significant advancements have been made in developing novel MRI techniques and contrast agents for biological research.

Purpose of the Study:

  • To review recent progress in molecular imaging using MRI.
  • To highlight key areas of development and their potential impact on biological and medical research.

Main Methods:

  • Review of current literature and research examples in molecular MRI.
  • Focus on specific applications including multimodality agents, receptor, apoptosis, and angiogenesis imaging.
  • Discussion of noninvasive cell tracking and MR marker gene imaging techniques.

Main Results:

  • Demonstration of successful applications of MRI in various molecular imaging domains.
  • Examples of innovative MR-optical agents enhancing multimodal imaging capabilities.
  • Progress in visualizing biological processes like apoptosis and angiogenesis at the molecular level.

Conclusions:

  • MRI is a versatile and evolving technology for molecular imaging.
  • Continued innovation in MRI agents and techniques promises deeper insights into biological processes.
  • Future applications may include enhanced diagnostics and therapeutic monitoring.