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Updated: Jun 25, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
[Percutaneous coronary intervention in the elderly]
Federico Costa1, Enrico Passamonti, Paolo Pedroni
1U.O. di Cardiologia, A.O. Istituti Ospitalieri, Cremona. fedecosta@tin.it
Insights
Elderly patients with acute coronary syndrome often receive less aggressive treatment. Percutaneous coronary intervention focuses on functional outcomes, not perfection, in older adults.
Area of Science:
- Cardiology
- Geriatric Medicine
- Interventional Cardiology
Context:
- Increasing elderly population in developed nations.
- Elderly patients constitute a significant portion of acute coronary syndrome admissions.
- Complex treatment due to comorbidities in older adults.
Purpose:
- To evaluate the safety and efficacy of percutaneous coronary intervention (PCI) in elderly patients.
- To address the undertreatment of elderly patients with non-ST-elevation acute coronary syndrome.
- To determine optimal revascularization strategies for older adults.
Summary:
- Elderly patients with non-ST-elevation acute coronary syndrome face undertreatment despite high-risk profiles.
- Percutaneous coronary intervention in the elderly is associated with increased risks of bleeding and renal failure.
- Revascularization goals for elderly patients should prioritize functional outcomes over complete anatomical success.
Impact:
- Highlights the need for tailored interventional strategies in geriatric cardiology.
- Informs clinical decision-making regarding percutaneous coronary intervention for older adults.
- Emphasizes the importance of functional status in assessing treatment success for elderly cardiac patients.
Abstract:
Developed countries are experiencing an unprecedented growth in the number of elderly citizens. Elderly patients represent one third of all admissions for non-ST-elevation acute coronary syndrome in the coronary care unit. Treatment is more complex due to comorbidities. The safety and efficacy of percutaneous coronary intervention in elderly patients have not been extensively studied. Despite their high-risk characteristics and worse outcomes, compared with younger patients, the elderly receive less aggressive treatments. The risk of major bleeding and renal failure are increased with percutaneous coronary intervention; in addition the functional condition remains an important concern. Revascularization in elderly patients is not to be aimed at perfection, but at functional results.
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