Body perfusion CT: technique, clinical applications, and advances

Area of Science:

• Radiology
• Medical Imaging
• Oncology

Background:

• Perfusion CT (PCT) has evolved significantly from research to clinical practice.
• PCT is increasingly vital in oncology for tissue characterization, risk assessment, and treatment response evaluation.
• Technological advancements are overcoming previous limitations in coverage and radiation dose.

Purpose of the Study:

• To review the fundamental principles and techniques of Perfusion CT.
• To discuss the diverse oncological and non-oncological clinical applications of Perfusion CT in body imaging.

Main Methods:

• Review of Perfusion CT principles and techniques.
• Discussion of clinical applications based on current literature and practice.

Main Results:

• Perfusion CT demonstrates significant progress and expanding clinical utility.
• Key applications include tissue characterization, risk stratification, and monitoring treatment effects in oncology.
• Emerging role in assessing early response to targeted therapies.

Conclusions:

• Perfusion CT is a valuable tool in modern clinical practice, particularly in oncology.
• Technological improvements enhance its feasibility and safety for broader application.
• The review covers essential principles, techniques, and diverse clinical uses in body imaging.