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Related Concept Videos

Allergic Drug Reactions01:27

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Allergic Reactions02:06

Allergic Reactions

Overview
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
Hypersensitivities01:30

Hypersensitivities

Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Hypersensitivity Reactions: Delayed Hypersensitivity Reactions01:29

Hypersensitivity Reactions: Delayed Hypersensitivity Reactions

Delayed-Type Hypersensitivity (DTH), or Type IV hypersensitivity, is a cell-mediated immune response. It occurs when T cells, rather than antibodies, mediate a reaction to specific antigens. It is characterized by a delayed onset (1-2 days) and involves the recruitment of macrophages to the inflammation site.The initiation of a DTH response begins with the sensitization of T cells. During this phase, which lasts at least 1-2 weeks, antigen-specific T cells are activated, clonally expanded, and...

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Related Experiment Video

Updated: Jun 25, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

["NPAs": a new allergic risk?].

G Dutau1, F Rancé

  • 1guy.dutau@wanadoo.fr

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|February 7, 2009
PubMed
Summary
This summary is machine-generated.

New pet animals (NPAs), including rodents, reptiles, and spiders, are increasingly recognized as significant allergens. Allergists and pediatricians play a key role in diagnosing and preventing these emerging pet allergies.

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Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation
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Last Updated: Jun 25, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
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Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation
04:34

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation

Published on: September 14, 2018

Area of Science:

  • Veterinary Medicine
  • Allergology
  • Zoology

Context:

  • The rise of "new pet animals" (NPAs) beyond traditional dogs and cats presents emerging health concerns.
  • NPAs encompass a diverse range of species, including rodents, birds, reptiles, amphibians, and arachnids.
  • Social trends and the demand for exotic pets contribute to the increasing prevalence of NPAs.

Purpose:

  • To review the growing issue of allergies associated with NPAs.
  • To highlight the diagnostic and preventive roles of allergists and pediatricians regarding NPA allergies.
  • To discuss the allergic risks posed by various NPAs, including rodents, reptiles, amphibians, and spiders.

Summary:

  • Classic pet allergens (dogs, cats) are now joined by NPAs, a broad category including rodents, reptiles, amphibians, and spiders.
  • These NPAs, driven by social trends for exotic pets, pose increasing allergic risks alongside potential physical dangers.
  • Allergists and pediatricians are crucial for managing and preventing allergies to these diverse new pet animals.

Impact:

  • Increased awareness among healthcare professionals and the public regarding NPA-related allergies.
  • Improved diagnostic strategies for identifying allergies to a wider range of animal species.
  • Guidance for pet selection to mitigate allergy risks, particularly for vulnerable populations.