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Updated: Jun 25, 2026

Real-time Breath Analysis by Using Secondary Nanoelectrospray Ionization Coupled to High Resolution Mass Spectrometry
Published on: March 9, 2018
Neutral desorption using a sealed enclosure to sample explosives on human skin for rapid detection by EESI-MS
1College of Chemistry, Biology, and Material Science, East China Institute of Technology, Fuzhou, PR China. chw8868@gmail.com
Abstract:
A novel air-tight neutral desorption enclosure has been fabricated to noninvasively sample low picograms of explosives 2,4,6-trinitrotoluene (TNT), hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), octahydro-1,3,5,7-tetranitro-1,3,5,7-tetraazocine (HMX), triacetone triperoxide (TATP), and nitroglycerin (NG) from human skin using a neutral nitrogen gas beam. Without further sample pretreatment, the explosive mixtures collected from the skin surface were directly transported by a nitrogen carrier gas over a 4-m distance for sensitive detection and rapid identification by extractive electrospray ionization tandem mass spectrometry.
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