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Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
09:45

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors

Published on: April 27, 2017

Urea, but not guanidinium, destabilizes proteins by forming hydrogen bonds to the peptide group

Woon Ki Lim1, Jörg Rösgen, S Walter Englander

  • 1Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104, USA.

Proceedings of the National Academy of Sciences of the United States of America
|February 7, 2009
PubMed

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