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Updated: Dec 21, 2025
09:21
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
12.4K
[Diagnosis and management for acute ischemic stroke].
1Department of Stroke Medicine, Kawasaki Medical School.
Rinsho Shinkeigaku = Clinical Neurology
|February 10, 2009
Summary
Intravenous tissue plasminogen activator (IV-t-PA) therapy is now a standard treatment for acute ischemic stroke within 3 hours of symptom onset in Japan. Early diagnosis and stroke unit care improve patient outcomes.
Area of Science:
- Neurology
- Cardiovascular Medicine
- Radiology
Context:
- The Japanese government approved intravenous tissue plasminogen activator (IV-t-PA) for acute ischemic stroke in 2005.
- Current clinical practice in Japan prioritizes IV-t-PA therapy for patients arriving within 3 hours of stroke onset.
Purpose:
- To outline the current management strategies for acute stroke in Japan.
- To emphasize the importance of timely diagnosis and treatment with IV-t-PA.
Summary:
- Accurate diagnosis involves systematic evaluation using CT/MRI, neurosonology (transcranial Doppler, carotid echography), echocardiography (TEE, TTE), SPECT, and angiography, focusing on heart and brain arteries.
- Recommended Grade A treatments include IV-t-PA therapy, aspirin administration within 48 hours, and stroke unit management.
- Stroke unit care is crucial for improving functional outcomes and reducing hospital stay duration.
Impact:
- The adoption of IV-t-PA has significantly changed acute stroke management in Japan.
- Evidence-based therapeutic approaches for acute stroke are rapidly evolving, necessitating continuous updates in clinical practice.
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