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Updated: Jun 25, 2026

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment
Published on: November 6, 2018
[Initial care of the severely burned patient]
Wolfgang Buhre1, Frank Wappler
1Division of Perioperative Care and Emergency Medicine, University Medical Center Utrecht. w.f.buhre@umcutrecht.nl
Abstract:
The care of severely burned patient is still an interdisciplinary challenge. Despite improvements in the understanding of the pathophysiology of burn disease, mortality is high if more than 25 % of body surface area is burned. Mortality increases in the presence of inhalation injury. Initially, the burn trauma leads to a capillary leakage syndrome, resulting in severe hypovolemia. Therefore, adequate volume substitution is the primary therapy to prevent potential life-threatening hypovolemic shock.
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