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Updated: Jun 25, 2026

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A Simple Mechanical Procedure to Create Limbal Stem Cell Deficiency in Mouse
Published on: November 17, 2016
Dyskeratosis congenita with corneal limbal insufficiency
Deniz Aslan1, Sengul Ozdek, Orhun Camurdan
1Section of Hematology, Department of Pediatrics, Faculty of Medicine, Gazi University, Ankara, Turkey. drdagutf@superonline.com
Pediatric Blood & Cancer
|February 10, 2009
Abstract:
We describe a newly diagnosed Turkish adolescent female with Dyskeratosis congenita along with the novel ocular finding of corneal limbal insufficiency. Corneal limbal insufficiency was suggested to be a premature aging sign resulting from a deficiency in corneal stem cell activity, a biological process caused by underlying telomeric defect in this disease.
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