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Updated: Jun 25, 2026

12:59
Derivation of Stem Cell Lines from Mouse Preimplantation Embryos
Published on: August 20, 2017
Distribution of human embryonic stem cell lines: who, when, and where
Jennifer B McCormick1, Jason Owen-Smith, Christopher Thomas Scott
1Division of General Internal Medicine, Program in Professionalism and Bioethics, Mayo Clinic, Rochester, MN 55905, USA. mccormick.jb@mayo.edu
Cell Stem Cell
|February 10, 2009
Abstract
No abstract available in PubMed .
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Embryonic Stem Cells
Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
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Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
Stem Cell Culture
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

