Related Experiment Video
Updated: Jun 25, 2026

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
Cancer and fecundity issues mandate a multidisciplinary approach
Dominique de Ziegler1, Isabelle Streuli, Ioannis Vasilopoulos
1Université Paris Descartes, Service de Gynécologie Obstétrique II et Médecine de la Reproduction, Paris, France. ddeziegler@orange.fr
Objective:
To review the existing options for preserving fecundity in young cancer patients, outlining the differences that exist in each individual cancer situation and how these affect our choice of fecundity-preserving measures.
Design:
Review the pathophysiology data on ovarian function that serve for outlining the advantages and/or drawbacks of certain fecundity-preserving measures such as ovarian freezing and emergency IVF. Provide support arguments for outlining the need for setting locally rooted cancer and fecundity task forces that throw the bases for a multidisciplinary approach in this field.
Setting:
Review of literature data.
Patient(S):
Women of reproductive age affected with different types of cancer.
Main Outcome Measure(S):
Outcome of selected emergency fertility preserving measures such as ovarian tissue freezing followed by grafting or emergency IVF.
Result(S):
When performed in the 30s-the typical age for breast cancer, the most frequently encountered cancer in women of reproductive age, ovarian freezing hampers ovarian recovery and the chances for spontaneous pregnancy.
Conclusion(S):
Based on a review of the different situations encountered, we recommend that fecundity-preserving measures offered to young cancer patients, including ovarian freezing and emergency IVF, emanate from multidisciplinary approaches.
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