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Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...

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Updated: Jun 25, 2026

Murine Full-thickness Skin Transplantation
07:59

Murine Full-thickness Skin Transplantation

Published on: January 2, 2017

Tuberculosis in a solid-organ transplant recipient: modern-day implications.

Ayad Jazrawi1, Makoto Jones, Abdallah G Kfoury

  • 1UTAH Cardiac Transplant Program, Salt Lake City, Utah, USA.

The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
|February 10, 2009
PubMed
Summary

Tuberculosis (TB) presents atypically in solid-organ transplant (SOT) recipients, posing a high mortality risk. This review covers TB diagnosis, treatment, and public health considerations in SOT patients.

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Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation
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Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation

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Last Updated: Jun 25, 2026

Murine Full-thickness Skin Transplantation
07:59

Murine Full-thickness Skin Transplantation

Published on: January 2, 2017

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation
11:49

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation

Published on: May 2, 2013

Area of Science:

  • Infectious Diseases
  • Transplantation Medicine
  • Public Health

Background:

  • Solid-organ transplant (SOT) recipients are immunocompromised, increasing susceptibility to opportunistic infections.
  • Tuberculosis (TB) poses a significant threat in SOT populations due to altered immune status.

Observation:

  • Clinical presentation and disease progression of TB in SOT recipients can be atypical.
  • Diagnosis of TB in SOT patients often requires a comprehensive approach utilizing various tests.

Findings:

  • Review of diagnostic modalities for TB in SOT recipients.
  • Analysis of anti-mycobacterial therapy specific to the SOT population.
  • Examination of public health implications associated with TB in SOT recipients.

Implications:

  • Optimizing TB diagnosis and management is crucial for improving outcomes in SOT patients.
  • Understanding TB's impact on SOT recipients is vital for infection control and public health strategies.
  • Early detection and appropriate treatment can mitigate the high mortality risk associated with TB in SOT recipients.