Perspectives on eGFR reporting from the interface between primary and secondary care

Area of Science:

• Nephrology
• Public Health
• Cardiovascular Medicine

Background:

• Automated reporting of estimated glomerular filtration rate (eGFR) using the Modification of Diet in Renal Disease (MDRD) equation is debated for its community-wide value.
• Concerns exist regarding the MDRD equation's inaccuracies in specific populations, potentially leading to a "worried well" phenomenon and resource implications.
• Chronic kidney disease significantly increases cardiovascular disease risk, yet risk factors are often inadequately managed.

Purpose of the Study:

• To evaluate the utility of eGFR reporting in risk stratification for cardiovascular disease.
• To explore the potential of eGFR reporting to improve patient outcomes in a broad population.
• To address concerns surrounding the use of eGFR as a "covert" screening tool.

Main Methods:

• Analysis of eGFR reporting data.
• Assessment of the MDRD equation's performance in diverse populations.
• Review of existing literature on chronic kidney disease and cardiovascular risk.

Main Results:

• The study posits that eGFR reporting provides an opportunity for risk stratification.
• Potential for improved patient outcomes through targeted management of cardiovascular risk factors in those identified by eGFR.

Conclusions:

• eGFR reporting, despite debates on the MDRD equation's accuracy, can be a powerful tool for identifying individuals at increased risk of cardiovascular disease.
• Leveraging eGFR data allows for proactive health management, potentially mitigating adverse outcomes and optimizing resource allocation.