Heads or tails: which is more important in molecular self-assembly?

Self-assembled monolayers can modify the functionality of the surfaces on which they assemble. Because they alter the surface properties, self-assembled monolayers can be used for a multitude of applications. Understanding the forces that drive the formation of a self-assembled monolayer on a given surface remains an important area of investigation. A new paper discusses some of the considerations for self-assembly on semiconductors. The results highlight the tradeoffs between achieving crystalline packing of the tail groups and forming commensurate bonding between the head groups and the underlying surface. Where the emphasis should be placed depends on the application, but obtaining both interfacial and intermolecular ordering may be possible.