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Doxycycline-induced pseudotumor cerebri.

James H Tabibian1, Miguel A Gutierrez

  • 1Division of Dermatology, Geffen School of Medicine at UCLA, Los Angeles, CA, USA. jhtabib@ucla.edu

Southern Medical Journal
|February 11, 2009
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Summary
This summary is machine-generated.

Doxycycline, a common acne treatment, can rarely cause pseudotumor cerebri (PTC). This case highlights the importance of physician and patient awareness of this rare side effect, even with this specific antibiotic.

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Area of Science:

  • Neurology
  • Dermatology
  • Ophthalmology

Background:

  • Tetracyclines are frequently prescribed for acne vulgaris.
  • Pseudotumor cerebri (PTC) is a known, albeit rare, side effect associated with tetracycline use.
  • Doxycycline is a commonly used tetracycline for acne treatment.

Observation:

  • A patient using oral doxycycline and topical retinoids for acne developed PTC within two months.
  • This case highlights a rare instance of doxycycline-induced PTC.
  • The patient experienced new-onset headaches and visual changes.

Findings:

  • The development of PTC in a patient treated with doxycycline and topical retinoids.
  • This case underscores the potential for doxycycline to cause PTC, despite its rarity.
  • Papilledema was observed during ophthalmologic examination.

Implications:

  • Physicians and patients should remain vigilant for PTC symptoms during doxycycline treatment for acne.
  • Early ophthalmologic examination for papilledema is crucial for diagnosing doxycycline-induced PTC.
  • Awareness of this rare adverse effect is important for managing acne vulgaris patients on doxycycline.