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Updated: Jun 25, 2026

Advanced Compositional Analysis of Nanoparticle-polymer Composites Using Direct Fluorescence Imaging
Published on: July 19, 2016
Systematic investigation of preparing biocompatible, single, and small ZnS-Capped CdSe quantum dots with amphiphilic
Robin E Anderson1, Warren C W Chan
1Institute of Biomaterials & Biomedical Engineering, Centre for Biomaterials and Biomolecular Research, University of Toronto, Toronto, ON, Canada.
Abstract:
The successful transfer of nanoparticles between solvents is critical for many applications. We evaluated the impact of amphiphilic polymer composition on the size, transfer efficiency, and biocompatibility of tri-n-octylphosphine oxide/hexadecylamine-stabilized semiconductor ZnS-capped CdSe and CdS-capped CdTe(x)Se(1-x) quantum dots (QDs). We also investigated the adsorption of various proteins onto the surface of these QDs and studied the effect of surface chemistry on non-specific protein binding. The results from these studies will have implications in the design of QDs and other nanoparticles for biological and biomedical applications.

