Related Experiment Video
Updated: Jun 25, 2026
04:36
An Assay to Detect Protection of the Retinal Vasculature from Diabetes-Related Death in Mice
Published on: January 12, 2024
[Myopic and retinopathy]
Li-bin Guo1, Xiao-hua Zheng, Jing-wen Wang
1Department of Ophthalmology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
|February 13, 2009
Summary
Myopic retinopathy affects 14.35% of patients, with peripheral lesions increasing with myopia severity and age. Posterior pole lesions occur in older, highly myopic individuals, necessitating careful fundus examination.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Myopia Research
Context:
- Myopic retinopathy is a significant complication of myopia.
- Understanding its incidence and risk factors is crucial for patient management.
Purpose:
- To investigate the incidence of myopic retinopathy and identify associated risk factors.
- To analyze the relationship between myopic retinopathy, diopter, age, and sex.
Summary:
- Retrospective analysis of 1449 myopic patients (2879 eyes) revealed a 14.35% incidence of myopic retinopathy.
- Peripheral retinal lesions (13.75%) increased significantly with higher diopters, older age, and in females.
- Posterior pole lesions (0.76%) were found in highly myopic patients (> -6.00 D) over 25 years old.
Impact:
- Highlights the increased prevalence of retinal lesions in myopic individuals compared to emmetropia.
- Emphasizes the need for regular fundus examinations in myopic patients for early detection and treatment.
- Provides data on specific risk factors (diopter, age, sex) for different types of myopic retinopathy.
Related Concept Videos
01:27Diabetic Retinopathy
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
01:22Photoreceptors and Visual Pathways
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
01:25Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
01:16Focusing of Light in the Eye
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
01:28Diabetic Nephropathy
Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...
01:27Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...